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PEA guards versus bacterial infection by using innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA at a dose of 0.one mg/kg body weight extended survival fee and lessened neuro-inflammation within an aged murine bacterial meningitis design, inside the absence of antibiotics [forty two].This can be a preview of member

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FM is usually a diffuse pathological affliction characterised by an augmented perception of ache and various connected indications, Particularly snooze disturbances and day-to-day tiredness. The latest etiopathogenetic theories handle neuroinflammation as A significant actor within the perseverance of central and peripheral sensitization in FM, lea

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